|(-;-)||2||less favorable clinical outcome when on antipsychotics|
|(-;C)||2||1.3x increased adenoma recurrence risk|
In a study of individuals in the Polyp Prevention Trial with any, multiple (>/=2) or advanced colorectal adenoma recurrence after 4 years, compared to those without adenoma recurrence, rs1799732(C;T) individuals were significantly associated with all adenoma recurrence (odds ratio 1.30, CI: 1.01-1.69). The authors speculate this increased risk of adenoma recurrence (and an association with colorectal cancer) may be related to SNP-associated differences in alcohol and fat intake.[19065655?dopt=Abstract PMID 19065655]
23andMe blog Alcoholism related
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[PMID 18563706] The impact of genetic variation in DRD2 and SLC6A3 on smoking cessation in a cohort of participants 1 year after enrollment in a lung cancer screening study.
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[PMID 19390575] Lung cancer susceptibility model based on age, family history and genetic variants.
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[PMID 20191112] The Genetics of Anorexia Nervosa: Current Findings and Future Perspectives.
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