||Very slightly increased (1.18x) increased breast cancer risk
|?|| (A;A) (A;G) (G;G) ||28|
rs997669 shows an association with breast cancer in a British study involving ~2300 patients. The odds ratio for the (G;G) vs (A;A) homozygotes is 1.18 (CI: 1.04-1.34, p=0.003).[PMID 18174243]
[PMID 19124506] Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
[PMID 19258477] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.
[PMID 27738493] Pathway analysis of bladder cancer genome-wide association study identifies novel pathways involved in bladder cancer development.